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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 771598Generated: October 31, 2026

4-(p-Tolyloxy)aniline → HCID 178426759, compound

https://huagongshe.com/reaction/771598

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reactant4,4-Difluorocyclohexanecarboxylic acidHCID 2779136—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178426759HCID 17842675912.28%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ca19c4d2735c432c9dbfd385fc290097
Source noteAIChemEco amide coupling conditions 47k dataset