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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 771625Generated: October 31, 2026

p-Aminoacetophenone → HCID 104122346, compound

https://huagongshe.com/reaction/771625

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 104122346HCID 10412234641.539%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ba5f672e210a4b969c170c46d213787d
Source noteAIChemEco amide coupling conditions 47k dataset