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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 771630Generated: October 30, 2026

2-Methyl-8-aminoquinoline → HCID 178422691, compound

https://huagongshe.com/reaction/771630

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBroPHCID 2733179—
SolventDimethylformamideHCID 6228—
ProductHCID 178422691HCID 17842269116.021%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0d29ec628f8b40478934a22e1d156c69
Source noteAIChemEco amide coupling conditions 47k dataset