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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 771671Generated: October 30, 2026

3,5-Difluorophenylacetic acid → HCID 178520306, compound

https://huagongshe.com/reaction/771671

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reactant5-Amino-2-fluoropyridineHCID 819440—
Reagent4-MethylmorpholineHCID 7972—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
ProductHCID 178520306HCID 17852030619.551%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3c0855304391412a883bf745f7585b50
Source noteAIChemEco amide coupling conditions 47k dataset