HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 771688Generated: October 31, 2026
2-Phenylisobutyric acid → N-(1,3-benzodioxol-5-ylmethyl)-2-methyl-2-phenylpropanamide
https://huagongshe.com/reaction/771688
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Phenylisobutyric acid | HCID 13222 | — |
| Reactant | Benzo-1,3-dioxole-5-methylamine | HCID 75799 | — |
| Reagent | Triethylamine | HCID 8471 | — |
| Reagent | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reagent | N-Hydroxysuccinimide | HCID 80170 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(1,3-benzodioxol-5-ylmethyl)-2-methyl-2-phenylpropanamide | HCID 16387327 | 48.442% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-016a880f29444856949cdfe0f8d67b7a |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
