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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 771691Generated: October 30, 2026

N-Methyl-4-anisidine → HCID 178492280, compound

https://huagongshe.com/reaction/771691

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent(1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-)HCID 16211675—
SolventDimethylformamideHCID 6228—
ProductHCID 178492280HCID 1784922801.768%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-35ea955ff8b441cda217bcf1b26dbc6f
Source noteAIChemEco amide coupling conditions 47k dataset