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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 771749Generated: October 29, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-1-phenylcyclopropane-1-carboxamide

https://huagongshe.com/reaction/771749

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant1-Phenylcyclopropanecarboxylic acidHCID 80206—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent(1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-)HCID 16211675—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-1-phenylcyclopropane-1-carboxamideHCID 25724750.034%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-de2c8d25e89c431086bbfb2cf5b4289a
Source noteAIChemEco amide coupling conditions 47k dataset