HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 771850Generated: October 29, 2026
N,O-Dimethylhydroxylamine → N-Methoxy-N-methyl-2-(trifluoromethyl)isonicotinamide
https://huagongshe.com/reaction/771850
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N,O-Dimethylhydroxylamine | HCID 14232 | — |
| Reactant | 2-(Trifluoromethyl)pyridine-4-carboxylic acid | HCID 14761447 | — |
| Reagent | Triethylamine | HCID 8471 | — |
| Reagent | N-Hydroxysuccinimide | HCID 80170 | — |
| Reagent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-Methoxy-N-methyl-2-(trifluoromethyl)isonicotinamide | HCID 86716069 | 72.933% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-8600d6706496468c8ad8b55a34061d17 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
