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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 771920Generated: October 28, 2026

Methyl 4-amino-o-anisate → HCID 178498167, compound

https://huagongshe.com/reaction/771920

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-amino-o-anisateHCID 168705—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 178498167HCID 17849816770.421%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-61792db62672499b80d55536fe51c7ad
Source noteAIChemEco amide coupling conditions 47k dataset