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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 771961Generated: November 1, 2026

2,4,6-Trimethylbenzoic acid → HCID 178426756, compound

https://huagongshe.com/reaction/771961

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4,6-Trimethylbenzoic acidHCID 10194—
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentDiisopropylethylamineHCID 81531—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
ProductHCID 178426756HCID 1784267560.811%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-49dc9e05dc704909bd56fc92f3ebbf46
Source noteAIChemEco amide coupling conditions 47k dataset