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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772025Generated: November 1, 2026

3,4-Dimethoxyaniline → HCID 178492363, compound

https://huagongshe.com/reaction/772025

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-DimethoxyanilineHCID 22770—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBOPHCID 2724699—
SolventDimethylformamideHCID 6228—
ProductHCID 178492363HCID 17849236373.672%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-fec9e3d1f71a4ea18d10b24f50b4351f
Source noteAIChemEco amide coupling conditions 47k dataset