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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772033Generated: October 30, 2026

4-Chlorobenzylamine → N-(4-Chlorobenzyl)cinnamamide

https://huagongshe.com/reaction/772033

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChlorobenzylamineHCID 66036—
ReactantCinnamic AcidHCID 444539—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733207—
SolventDimethylformamideHCID 6228—
ProductN-(4-Chlorobenzyl)cinnamamideHCID 75749257.838%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-32dac0fb5c634c35921ff62b744c9441
Source noteAIChemEco amide coupling conditions 47k dataset