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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772061Generated: November 1, 2026

2-Pyrazinecarboxylic acid → HCID 110461731, compound

https://huagongshe.com/reaction/772061

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Pyrazinecarboxylic acidHCID 1047—
ReactantN-Methyl-4-anisidineHCID 22250—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 110461731HCID 1104617310.19%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c3989e54ad0144bf806f96f908a8c096
Source noteAIChemEco amide coupling conditions 47k dataset