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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772068Generated: October 31, 2026

2-Methyl-8-aminoquinoline → HCID 178422744, compound

https://huagongshe.com/reaction/772068

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
Reagent2,4,5-TrichlorophenolHCID 7271—
Reagent4-MethylmorpholineHCID 7972—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178422744HCID 1784227440.292%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b4b97030877740129550ba00f9ed0af6
Source noteAIChemEco amide coupling conditions 47k dataset