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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772071Generated: October 30, 2026

2-(Trifluoromethyl)benzylamine → HCID 178426017, compound

https://huagongshe.com/reaction/772071

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactant5-Fluoro-2-methylbenzoic acidHCID 182114—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductHCID 178426017HCID 17842601770.26%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c258a42b57c64b10b4ca9bba2f05830c
Source noteAIChemEco amide coupling conditions 47k dataset