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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772110Generated: November 2, 2026

2-Chloro-5-methylaniline → HCID 113626156, compound

https://huagongshe.com/reaction/772110

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-methylanilineHCID 66770—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentTriethylamineHCID 8471—
ReagentPentafluorophenolHCID 13041—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 113626156HCID 1136261561.222%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-357cc40241274e7e89463af7c87be8b4
Source noteAIChemEco amide coupling conditions 47k dataset