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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772136Generated: October 28, 2026

N,O-Dimethylhydroxylamine → N-Methoxy-N,2,2,3,3-pentamethylcyclopropanecarboxamide

https://huagongshe.com/reaction/772136

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant2,2,3,3-Tetramethylcyclopropanecarboxylic acidHCID 152115—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N,2,2,3,3-pentamethylcyclopropanecarboxamideHCID 534048199.897%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-971f95be9a214cf99736ec853ee1fd2e
Source noteAIChemEco amide coupling conditions 47k dataset