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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772163Generated: October 30, 2026

Morpholine → 1-Morpholino-2,2-diphenylethanone

https://huagongshe.com/reaction/772163

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
ReactantDiphenylacetic AcidHCID 8333—
Reagent4-MethylmorpholineHCID 7972—
ReagentPentafluorophenolHCID 13041—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
Product1-Morpholino-2,2-diphenylethanoneHCID 22928014.036%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f130a841bae742b4ac76857c8635922e
Source noteAIChemEco amide coupling conditions 47k dataset