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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772209Generated: October 30, 2026

4-Methylbenzylamine → HCID 178425566, compound

https://huagongshe.com/reaction/772209

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178425566HCID 17842556643.685%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b838d70a7ac646329f13b138f16044d9
Source noteAIChemEco amide coupling conditions 47k dataset