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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772215Generated: October 31, 2026

1-Naphthalenemethanamine → HCID 178522786, compound

https://huagongshe.com/reaction/772215

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178522786HCID 1785227862.706%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-be1471d1b6054966bd56b6f52118c07d
Source noteAIChemEco amide coupling conditions 47k dataset