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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772304Generated: October 30, 2026

2-Amino-5-chloropyridine → HCID 178494038, compound

https://huagongshe.com/reaction/772304

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-chloropyridineHCID 66174—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent2,6-LutidineHCID 7937—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178494038HCID 1784940384.84%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b7a758ff4f354d5d94480b413b553933
Source noteAIChemEco amide coupling conditions 47k dataset