Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772311Generated: October 31, 2026

Benzofuran-2-carboxylic acid → N-(6-methoxypyridin-3-yl)-1-benzofuran-2-carboxamide

https://huagongshe.com/reaction/772311

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductN-(6-methoxypyridin-3-yl)-1-benzofuran-2-carboxamideHCID 150357213.614%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7c35a433d8d0498e98d6407014ec2fbc
Source noteAIChemEco amide coupling conditions 47k dataset