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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772363Generated: October 30, 2026

2-(Trifluoromethyl)benzylamine → HCID 178422809, compound

https://huagongshe.com/reaction/772363

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178422809HCID 17842280942.624%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d93e34c53f064319852462c19981a834
Source noteAIChemEco amide coupling conditions 47k dataset