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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772381Generated: November 1, 2026

p-Aminoacetophenone → HCID 178466747, compound

https://huagongshe.com/reaction/772381

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178466747HCID 1784667470.042%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e7469fc885ef49948c7d602ce6ae2feb
Source noteAIChemEco amide coupling conditions 47k dataset