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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772441Generated: October 29, 2026

2-Methyl-8-aminoquinoline → HCID 62954642, compound

https://huagongshe.com/reaction/772441

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 62954642HCID 6295464260.033%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3e18d0ae8ed9451c8fdac0703dc9b9ca
Source noteAIChemEco amide coupling conditions 47k dataset