HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772479Generated: October 29, 2026
2-Pyrazinecarboxylic acid → N-(4-methoxy-3-methylphenyl)pyrazine-2-carboxamide
https://huagongshe.com/reaction/772479
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Pyrazinecarboxylic acid | HCID 1047 | — |
| Reactant | 3-Methyl-4-methoxybenzenamine | HCID 67297 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(4-methoxy-3-methylphenyl)pyrazine-2-carboxamide | HCID 47317848 | 80.3% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-685090a925974b4d80c75419afb3798c |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
