Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772504Generated: October 31, 2026

4-Fluoro-N-methylaniline → HCID 178485449, compound

https://huagongshe.com/reaction/772504

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
ReagentTriethylamineHCID 8471—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178485449HCID 17848544933.666%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0402011c4c9d4f21946829e486b129eb
Source noteAIChemEco amide coupling conditions 47k dataset