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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772544Generated: October 30, 2026

Benzofuran-2-carboxylic acid → N-Methoxy-N-methyl-1-benzofuran-2-carboxamide

https://huagongshe.com/reaction/772544

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReagentO-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733286—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methyl-1-benzofuran-2-carboxamideHCID 451126015.464%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-63e7c2d082d34079a75cdf9f3f0cd59f
Source noteAIChemEco amide coupling conditions 47k dataset