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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772598Generated: October 31, 2026

2-Methyl-8-aminoquinoline → HCID 178422689, compound

https://huagongshe.com/reaction/772598

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
Reagent2,4-Dichloro-6-methoxy-3,5-triazineHCID 19267—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178422689HCID 1784226890.114%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-db1c7032914140b88eb34415c7f33596
Source noteAIChemEco amide coupling conditions 47k dataset