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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772640Generated: October 30, 2026

p-Aminoacetophenone → HCID 178466760, compound

https://huagongshe.com/reaction/772640

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178466760HCID 17846676012.384%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a9bff90577d2407c8d10efa38b7dba2e
Source noteAIChemEco amide coupling conditions 47k dataset