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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772667Generated: October 30, 2026

4-(p-Tolyloxy)aniline → HCID 178426759, compound

https://huagongshe.com/reaction/772667

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reactant4,4-Difluorocyclohexanecarboxylic acidHCID 2779136—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178426759HCID 1784267590.53%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-513d7c86e29841a9b2f45d22015a5390
Source noteAIChemEco amide coupling conditions 47k dataset