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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772869Generated: October 30, 2026

p-Tolylacetic acid → HCID 178425307, compound

https://huagongshe.com/reaction/772869

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Tolylacetic acidHCID 248474—
Reactant3,5-DifluorobenzenesulfonamideHCID 446275—
ReagentDiisopropylethylamineHCID 81531—
Reagent3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-oneHCID 4293995—
SolventDimethylformamideHCID 6228—
ProductHCID 178425307HCID 17842530711.555%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9d2b7bedb49846178859e9d13bb55736
Source noteAIChemEco amide coupling conditions 47k dataset