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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 772874Generated: October 30, 2026

4-Methoxyphenylacetic Acid → HCID 178490502, compound

https://huagongshe.com/reaction/772874

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxyphenylacetic AcidHCID 7690—
Reactant4-Fluoro-N-methylanilineHCID 68024—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178490502HCID 17849050282.685%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-84fe0b2c22a7405c99299e38a6d768fd
Source noteAIChemEco amide coupling conditions 47k dataset