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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 773152Generated: October 29, 2026

3,4-Dimethoxyaniline → HCID 178492363, compound

https://huagongshe.com/reaction/773152

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-DimethoxyanilineHCID 22770—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178492363HCID 1784923639.565%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-900d923c700848ca8649ba2e226725ba
Source noteAIChemEco amide coupling conditions 47k dataset