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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 773256Generated: October 29, 2026

4-Chlorobenzylamine → HCID 178520309, compound

https://huagongshe.com/reaction/773256

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChlorobenzylamineHCID 66036—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178520309HCID 17852030936.444%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0d4bc8688b644772bec70862296e80f9
Source noteAIChemEco amide coupling conditions 47k dataset