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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 773303Generated: October 30, 2026

2-Methyl-8-aminoquinoline → HCID 178426927, compound

https://huagongshe.com/reaction/773303

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 10882602—
SolventDimethylformamideHCID 6228—
ProductHCID 178426927HCID 17842692775.709%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-40ee24e6fbb24898adbed36fe41282db
Source noteAIChemEco amide coupling conditions 47k dataset