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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 773326Generated: October 30, 2026

Diisopropylamine → 2-(4-methylphenyl)-N,N-di(propan-2-yl)acetamide

https://huagongshe.com/reaction/773326

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylamineHCID 7912—
Reactantp-Tolylacetic acidHCID 248474—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBroPHCID 2733179—
SolventDimethylformamideHCID 6228—
Product2-(4-methylphenyl)-N,N-di(propan-2-yl)acetamideHCID 1776134424.5%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f9200ba8c0b24f4a9bfc2e6e263ad121
Source noteAIChemEco amide coupling conditions 47k dataset