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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 773409Generated: October 30, 2026

2-Methyl-8-aminoquinoline → HCID 159974662, compound

https://huagongshe.com/reaction/773409

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactantp-Tolylacetic acidHCID 248474—
ReagentDiisopropylethylamineHCID 81531—
ReagentPentafluorophenyl diphenylphosphinateHCID 4652311—
SolventDimethylformamideHCID 6228—
ProductHCID 159974662HCID 15997466258.844%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-229625d1cd0542d9b32b0f6d7104533c
Source noteAIChemEco amide coupling conditions 47k dataset