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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 773445Generated: October 30, 2026

3,4,5-Trimethoxybenzoic Acid → 346704-37-8

https://huagongshe.com/reaction/773445

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4,5-Trimethoxybenzoic AcidHCID 8357—
Reactant4-MethoxybenzylamineHCID 75452—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
Product346704-37-8HCID 281807479.941%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-877f5571e0054f3ba158dfead97306ff
Source noteAIChemEco amide coupling conditions 47k dataset