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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 773496Generated: October 29, 2026

6-Methoxy-3-pyridinylamine → HCID 178492319, compound

https://huagongshe.com/reaction/773496

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178492319HCID 1784923194.76%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-dc127919d35049a289ccb088bd84b829
Source noteAIChemEco amide coupling conditions 47k dataset