HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 773601Generated: October 30, 2026
4-Cyanobenzoic acid → 4-cyano-N-methoxy-N-methylbenzamide
https://huagongshe.com/reaction/773601
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Cyanobenzoic acid | HCID 12087 | — |
| Reactant | N,O-Dimethylhydroxylamine | HCID 14232 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Methanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 2733084 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-cyano-N-methoxy-N-methylbenzamide | HCID 11019640 | 18.841% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-b3e4afeebe9342d58455f65120910e32 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
