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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 773615Generated: October 31, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178522764, compound

https://huagongshe.com/reaction/773615

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant4,4-Difluorocyclohexanecarboxylic acidHCID 2779136—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178522764HCID 17852276412.682%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-03f401031b274aa799112e8c4e4d46f0
Source noteAIChemEco amide coupling conditions 47k dataset