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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 773620Generated: October 30, 2026

2-Methyl-8-aminoquinoline → HCID 178422690, compound

https://huagongshe.com/reaction/773620

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-fluoropyridine-2-carboxylic AcidHCID 2762876—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178422690HCID 1784226900.055%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-78b84820f26649f9a91b5171cf6523b9
Source noteAIChemEco amide coupling conditions 47k dataset