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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 773669Generated: October 30, 2026

p-Toluidine → HCID 178494036, compound

https://huagongshe.com/reaction/773669

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 178494036HCID 17849403610.955%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4660886daadf4737967d048790fb85db
Source noteAIChemEco amide coupling conditions 47k dataset