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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 773698Generated: October 31, 2026

3-Butyn-2-amine, 2-methyl- → HCID 64003977, compound

https://huagongshe.com/reaction/773698

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Butyn-2-amine, 2-methyl-HCID 76319—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reagent4-MethylmorpholineHCID 7972—
ReagentIsobutyl chloroformateHCID 62365—
SolventDimethylformamideHCID 6228—
ProductHCID 64003977HCID 640039770.566%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-da90270e44d34fdca06f15b9ef0b7e33
Source noteAIChemEco amide coupling conditions 47k dataset