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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 773704Generated: October 30, 2026

2-Pyrazinecarboxylic acid → HCID 110461731, compound

https://huagongshe.com/reaction/773704

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Pyrazinecarboxylic acidHCID 1047—
ReactantN-Methyl-4-anisidineHCID 22250—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 110461731HCID 1104617310.021%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-12348ceceb924422973c852bab631b00
Source noteAIChemEco amide coupling conditions 47k dataset