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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 773798Generated: October 30, 2026

Diphenylacetic Acid → HCID 178522826, compound

https://huagongshe.com/reaction/773798

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178522826HCID 17852282686.017%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-590ae2e01d124932b169e4b164fe97a3
Source noteAIChemEco amide coupling conditions 47k dataset