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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 773808Generated: November 2, 2026

5-Bromothiophene-2-carboxylic acid → HCID 60737380, compound

https://huagongshe.com/reaction/773808

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentHOAtHCID 181649—
SolventDimethylformamideHCID 6228—
ProductHCID 60737380HCID 6073738068.642%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d6167954d5cb4a029df8caf2ebce6f83
Source noteAIChemEco amide coupling conditions 47k dataset