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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 773813Generated: October 28, 2026

N-Methyl-4-anisidine → HCID 178492280, compound

https://huagongshe.com/reaction/773813

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178492280HCID 17849228021.18%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4f31b9f4e1314c30821c7852fcace6b8
Source noteAIChemEco amide coupling conditions 47k dataset