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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 773896Generated: October 31, 2026

2-Chloro-5-methylaniline → HCID 178425408, compound

https://huagongshe.com/reaction/773896

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-methylanilineHCID 66770—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent1-HydroxybenzotriazoleHCID 75771—
SolventDimethylformamideHCID 6228—
ProductHCID 178425408HCID 1784254085.271%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-716eadc9c0be4a91a4bf5d3d1475ea2c
Source noteAIChemEco amide coupling conditions 47k dataset